Christians serious about sanctification (the crisis and process of being made holy) will always feel a bit detached from this world system. They know this isn't the Kingdom they belong to; this isn't the ultimate allegiance they pledge to. Their values and priorities are out of sync with (and unappreciated by) the world. Consequently they will feel out of sorts in this world. The Bible says Christ followers are travelers who aren't home yet (1 Peter 2.11-12).
"We know that we are of God, and the whole world is under the sway of the evil one. And we know that the Son of God has come and has given us understanding so that we may know the true one. We are in the true one — that is, in his Son, Jesus Christ. He is the true God and eternal life."
1 John 5:19-20 CSB